COURTNEY SNYDER MD - HOLISTIC PSYCHIATRIST
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Lunch with Dr. William Walsh - His Story, Discoveries & the Future of Nutrient-Based Psychiatry

7/1/2016

26 Comments

 
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Courtney Snyder, MD

I first met Dr. Walsh in the fall of 2014, at his second physician training course here in the US.  At the time, I was uncertain how useful nutrients would be in my psychiatric practice.  What I learned seemed too good to be true. Upon returning home, I gradually began evaluating and treating specific nutrient imbalances in adults and children with depression, ADHD, anxiety, bipolar disorder, autism and other conditions. To my repeated surprise, most patients - children and adults alike improved… significantly - some dramatically, including those whose symptoms had failed to respond to other treatments.  

My interest grew. I wanted to learn more about Dr. Walsh’s story, his discoveries and his thoughts on the future of psychiatry.  I also wanted to express my gratitude.  Aside from the impact on my career, Dr. Walsh’s work has been pivotal in my own healing, and my daughter’s.  Lastly, I wanted to understand how those of us trained (now around 150 in the US and 500 internationally) might raise the visibility of his work, so more doctors could learn and more people could benefit.  This article is my attempt to do that.  Dr. Walsh generously met with me over lunch in Naperville, Illinois, not far from his office.  

***

If we are given three acts to live out our lives, Dr. Walsh has and continues to use each to its fullest potential.  His story is one of relentless curiosity, hard work, and fruitful collaborations.  As I spoke to him in this less formal setting, I came to appreciate his deep sense of purpose and compassion - a compassion born out of his own painful experiences involving family members who significantly benefitted from nutrient therapies.  

Dr. Walsh started on his professional path at the Institute of Atomic Research at Los Alamos Scientific Lab before obtaining his PhD in chemical engineering….not medicine…. not neuroscience...and not nutrition. Like many pioneers, his “outsider” background provided him a fresh perspective - one unencumbered by conventional thinking.  

He went on to Argonne National Laboratory and with an interest in crime and violence, began volunteering at the Stateville Penitentiary in Illinois.  There he eventually led 125 volunteers and launched an ex-offender program.  It was through this program, he met prisoner’s parents who would plant the seeds of his earliest discoveries.

Many of the prisoners, he noticed, came from well functioning families, not families struggling with trauma, poverty or other adversity.  Some parents recalled knowing there was something wrong with their child as early as the age of two.  They had other children who were thriving.  Why are some more vulnerable to criminal behavior from their very beginnings?  

With this curiosity, Dr. Walsh met Carl Pfeiffer, MD - at the time, the world’s leading expert in nutritional science. On they day they met, Dr. Pfeiffer was nominated for the Nobel Prize. They would collaborate for the next 12 years.  Dr. Walsh brought ex-convicts just out of prison, Dr. Pfeiffer analyzed their biochemistry and together they developed individualized treatment programs.   

By 1989, Dr. Walsh, along with physician colleagues, opened the Pfeiffer Treatment Center, where they began using Dr. Pfeiffer’s nutrient therapies to treat violent behavior in children.  When coexisting ADHD symptoms and learning problems started to disappear as well, they expanded their work, eventually to include depression, anxiety, bipolar disorder, schizophrenia, autism (and in more recent years Alzheimer's and Parkinson's).  In 18 years, they evaluated and treated 30,000 patients.  This resulted in 3 million chemistries -  the world's largest database on nutrient levels in individuals with mental disorders.  Within this were nutrient levels on more specific populations, ie. 3600 individuals with depression. Dr. Walsh has seen 6500 autistic children, more than anyone in the world.  His database even includes 25 serial killers and mass murders.  He’s  assisted the FBI and Scotland Yard and has designed nutritional programs for Olympic and professional athletes.

Though there are more than one thousand nutrients important in the body,  Dr. Walsh found, as he says, "..only about six or seven ...seem to have a dramatic impact on mental health. I used to be bothered by the fact that the same chemical imbalances kept turning up in different conditions.... It turns out that each of these nutrient factors is directly involved in either the synthesis or the epigenetic regulation of a neurotransmitter in the brain. That was really good news. If we had to study over 200 possible chemical imbalances and cor­rect whatever we found, designing treatments would be very difficult. Fortunately, we can focus on six or seven nutrients, and by balancing them, we can help most people with mental disorders."  

But, there was more,   Dr. Walsh discovered that most types of psychiatric conditions are epigenetic, meaning they involve a sudden change not in the gene itself, but in the functioning of a gene(s).  Epigenetic conditions typically don’t go away.  This change in functioning occurs as the result of an environmental insult either in utero or later in life.

Dr. Walsh's work has yielded more discoveries than can fit in this article.  Here are a few:


  • 70% of people with serious psychiatric conditions have a methylation imbalance - relative to 30% of the general population.  Such an imbalance can occur if there is too little (undermethylation) or too much methyl (overmethylation) - a molecule that comes from methionine which is present in protein. Methyl dominates gene expression.  More specifically, 95% of individuals with autism, OCD and antisocial personality are undermethylated.
  • 90% of people diagnosed with a mental disorder have either low-normal levels or are deficient in zinc. This nutrient is not difficult to measure, nor to normalize.
  • There are 5 biochemical phenotypes of depression - undermethylation, overmethylation, copper overload, pyroluria and toxic metals.  This explains the different responses to antidepressants such as SSRI’s (serotonin reuptake inhibitors).  Some people get worse.  Some don’t respond at all.  Getting worse can mean suicide or even homicide.  A young man carrying out a school shooting not long after being put on an antidepressant is likely overmethylated (folate deficient).  They can be identified by an inexpensive blood test, and be treated with a different family of medication, or more ideally, treated with folate, cyanocobalamin and niacin-amide.
  • Similarly there are biotypes for schizophrenia and ADHD, each requiring different treatments.  
  • Overwhelmingly, women with postpartum depression have elevated copper levels. This relates to the close relationship between estrogen and copper.  In Dr. Walsh’s outcome study of hundreds of women with postpartum depression, 85% improved after copper levels were normalized using nutrient protocols.  

In his years of experience, he says that more than 80% of people with ADHD and depression report significant improvement within three months and that more than 70% can eventually wean off psychiatric medication without a return of symptoms.

For more information, “Nutrient Power: Heal Your Biochemistry and Heal Your Brain.” by William Walsh, PhD

So what do you do when you have answers that could impact one of the biggest health crises in the modern world?   Well, if you’re Dr. Walsh, you consider the words of Gandhi: “When the people lead, the leaders will follow.”  He started the Walsh Research Institute with one goal being to train 1,000 physicians around the world in his advanced nutrient protocols.  He explained to me his thinking.  If he trains 1,000 doctors and they each treat 2,000 people,  then 2 million people could potentially benefit and go on to share their experience.  Eventually the leaders will follow.    

If Dr. Walsh’s nutrient protocols are so effective, why hasn’t conventional medicine gotten on board? Though Dr. Walsh has spoken at the American Psychiatric Association Annual Meeting and his physician training is certified by the American Medical Association for Continuing Medical Education, there are still obstacles. Unlike research into psychiatric medications, which is well funded through the pharmaceutical industry, research into nutrient therapies doesn’t have a strong profit motive.  Equally problematic is the standards of current research which address one variable at a time.  Our bodies and biochemistry are more complicated than this model allows.  Rarely does someone have just one nutrient imbalance.  Nutrient protocols/treatments are individualized and involve multiple nutrients/multiple variables which is quite different from one medication to treat one disorder.  This later type of research makes even less sense when you understand that one disorder, for example, depression, is actually at least 5 different disorders.

Such obstacles don’t seem to deter Dr. Walsh.  Nor does his age.  “You know, ...I’m old,” he says.  I hear this as a humorous comment on the number of years he’s been here and not a comment on his level of engagement in his work and life.

How could we have an impact sooner - before an environmental insult starts an epigenetic disorder? How could we identify those at risk?  Some forms of autism start in utero, however, there are a large number of infants who start out with normal development and then regress into autism. An environmental insult such as an infection or toxic exposure may result in an alteration in gene expression.  Dr. Walsh hopes to look at where on the DNA these epigenetic changes are occurring.  Knowing this could help identify future infants at risk, so that interventions could be made to prevent an epigenetic event and thus autism.

Not unrelated, Dr. Walsh describes a time when there will be a simple test done during routine physicals to identify those on the verge of an epigenetic disorder.  Proactive treatments, ie. nutrient therapies, could then be given to prevent many disorders from ever beginning.  Dr. Walsh’s upcoming ebook will discuss cancer, heart disease, autism, PTSD and other epigenetic conditions.  

Treatment and prevention of epigenetic disorders, however, isn’t a cure. While many of us are catching up to the reality that nutrients can impact genetic expression, Dr. Walsh is attending conferences on the latest cancer research. He’s listening closely to researchers who in their labs are resetting those epigenetic bookmarks that have been altered.  This essentially is what is required to cure cancer and other epigenetic disorders.  It is unknown how long it will take before this science makes its way into clinical practice.  Here again, the bulk of research dollars goes toward developing more pharmacotherapies, in this case chemotherapies.

***

Before our chat ends with Dr. Walsh returning to his own research, I wonder out loud, “With less than 500 doctors in the world using his nutrient protocols, who will carry on this type of research?”  Of those trained by the Walsh Research Institute, most of us are practitioners, not researchers.  He notes there are a few trained MD’s who also have their PhD’s (and thus have trained in research) and a few physicians who are already taking a leadership role in the Walsh Research Institute online group discussions. Mostly, however, he doesn’t know, nor does he seem particularly concerned. I think instead he’s wisely focused on the more impactful questions of the day - the questions he’d like to get answered - questions that could make all the difference in the life of a child or an adult and their families.


26 Comments
Sharleen Birkimer
7/1/2016 04:02:03 pm

Where are the research results in refereed nutrition journals?

Reply
Courtney Snyder, MD link
7/1/2016 04:54:11 pm

Sharleen, I'd reccommend the Walsh Research Institute Research/Study page which is at: http://www.walshinstitute.org/researchstudies.html

Reply
Leslie
7/6/2016 11:33:54 am

What are the nutrients Dr. Walsh refers to in this statement: "Fortunately, we can focus on six or seven nutrients, and by balancing them, we can help most people with mental disorders."

Reply
Courtney Snyde, MD link
7/6/2016 01:29:13 pm

Hi Leslie. Dr. Walsh refers to the primary "repeat offenders" as copper overload, vitamin B6 deficiency, zinc deficiency, methyl/folate imbalances, pyrrole disorder and fatty acid imbalances.

Reply
Johnny Atman link
7/6/2016 02:46:47 pm

The Orthomolecular approach is being used and developed alongside as Dr Walsh will only train GP's. There are other professionals that are now trained by Dr Lynch, Dr Rostenberg etc. I wish that we would merge and not work as standalone, but politics win, at the end of the day.

Reply
Courtney Snyder, MD link
7/6/2016 04:36:14 pm

Hi Johnny. You bring up a good point - Dr. Walsh has chosen to make the few training conferences (which are fairly small in size) available to only MD's, DO's and ND's. Though we didn't talk about this directly, I believe he addresses his reasoning in his book, "Nutrient Power." His choice to do this - at least in the short term- does limit the number of people who have access to his protocols. As far as not "merging" I guess I haven't thought of it as politics. I think there are some very important differences. Dr. Walsh's data, conclusions and protocols are very specific to brain related disorders, and though addressing methylation imbalances is a big part of Dr. Walsh's work, it is not done by identifying snps which Dr's Lynch and Rostenberg's work seems to involve a great deal of. For myself and I suspect many others, it comes down to integrating as many pieces that seem to be the most helpful for the particular patients we/they are working with. Thank you for your comment.

Reply
Michele
2/9/2019 07:07:02 pm

I have met Dr Walsh and he is a brilliant, kind man. His research literally saved the life of my then 7 yr old son who had severe mood issues. Fast forward 10 years under the care of Mensah Medical; no traces of my son’s past issues and he remains on his nutrient program brilliantly designed by Mensah. Regard Lynch and his associates - I find it quite DANGEROUS by indentifying SNPS and ignoring tests that clearly identify if one is over or undermethylated. He is nowhere even CLOSE to the work of Walsh, Dr Mensah and Dr Bowman and it shocks me people actually put up with his “treatment” Dr Walsh explains well why using SNPS to identify methylation issues is incomplete. And with the many supplements Lynch and his peers sell, they are nicely making money. I am shocked that more people are not alarmed by his choice of treatment. I recently came across a comment he made to a man questioning his treatment who obviously had been suffering for years. It was a flip, rude, pompous reply - I was stunned! Never EVER would Walsh, Bowman or Mensah treat a potential patient so rudely. We NEED to continue to promote Walsh’s work and that of Mensah Medical and related practioners to the public so they can be educated PROPERLY!!! Thank you!!!

Reply
Courtney Snyder link
2/13/2019 06:39:31 pm

Thank you Michele. Great to read how much your son has benefitted from the work of Dr’s Walsh, Mensah and Bowman. I’m obviously greatly value these approaches, but I have found Dr. Lynch’s work to be helpful in some situations. I agree with you that relying too heavily on SNPs is a problem. It does seem, that Dr. Lynch’s own thinking has evolved in these areas, in that he now speaks more about the potential expression of snps. Thank you for commenting.- Courtney

Dominic Pukallus link
7/7/2016 06:05:46 pm

Great article. I owe my new found life to Dr Walsh and his predecessors. You spelt Dr Pfeiffer's name wrong btw, the only quibble I'd have. Was he really nominated for a Nobel? Dr Hoffer should definitely have received one if this were a just world, perhaps even Linus Pauling his third. I'll be really happy if Dr Walsh ever gets one but then I'm biased.
Continuing what Johnny Atman said, it is now my goal, at the age of 47, to get my MD and train with Dr Walsh (or his successor by the time I'm qualified). In the case I were unable to graduate as an MD my next choice would be Naturopathy or Orthomolecular Nutrition but I'd be precluded from the Walsh training unless a modified form is made available to those.
I understand that at the moment there is concern that getting the approach accepted in the mainstream means that there is a certain guardianship of the 'brand' with respect to the perceived competence of the practitioners, and their scientific credibility. One hopes that this will become less of an issue once the required boxes have been ticked. Keep up the good fight.

Reply
Courtney Snyder, MD link
7/8/2016 09:43:40 am

Thank you Dominic and thank you for the spelling correction. Yes - Dr. Walsh also mentions the Nobel nomination on pg. 17 of "Nutrient Power."

Your experience and knowledge, I suspect, are already having a great impact on the lives of others. Best to you in whichever direction your path takes you. Thanks again.

Reply
Annajane link
7/9/2016 04:41:00 pm

Thanks so much for the précis of his concept. Having pyorulia and copper issues and having been episodically depressed it's great to be clear about the connection

Reply
Courtney Snyder, MD link
7/11/2016 11:02:20 am

Thanks you - Glad this was helpful.

Reply
Glenn A
10/30/2016 01:50:34 pm

Thanks for this great interview to bring us up to date on Dr. William Walsh! I often get questions from others regarding why Walsh, as represented in his book, doesn't speak about methyl folate and methyl cobolamine, a couple of the "new" forms of vitamins available for treatment of mental disorders. It's nice to have your interview on hand to show that Walsh is staying current and not just reading, but also does studies via his institute to further the knowledge base on treating mental disorders.

I found this interview very enlightening along these lines. Walsh mentions some new insights gained recently via his studies -- things I hadn't heard anywhere else:

https://thequantifiedbody.net/episode-2-optimizing-brain-biochemistry-with-william-j-walsh/

Glenn

Reply
Courtney Snyder link
5/12/2017 12:45:08 pm

Thank you, Glenn. And yes, I can assure you that Dr. Walsh is staying very current, in fact, he has a new book that is about to come out.

Reply
Ellen
6/4/2017 06:52:17 pm

Is the ebook out? I am particularly interested on ptsd findings by dr walsh

Courtney Snyder link
6/5/2017 08:26:00 am

Hi Ellen. I don't believe the ebook is out yet. But if and when I hear, I will try to let you know. The book that is supposed to come out shortly, relates to Bipolar Disorder. I hope you see this - for some reason, I'm unable to reply to your note below.

Susan Cristallee
1/17/2017 07:09:28 pm

What a lovely blog post! So, mental health awareness is something that I would like to speak about. I'm taking a workshop on Public Speaking, and the information that is in this article has a ton of points that need to pointed out to the masses. Are there any conferences, industry events, or professional associations where it would be a good place to speak on this topic specifically. I think I am going to do my part to create a talk that can be given at any conference that promotes conscious living. Thanks for any feedback!

Reply
Courtney Snyder link
5/12/2017 12:50:12 pm

Susan,
Apologies for this very delayed response. I do hope that you have pursued your interest in this topic and have had some opportunities to speak. Because the topics of mental health, mental illness and brain related symptoms touch everyone lives directly or indirectly, I don't think you can go wrong. I would say to stay open to opportunities that are right in front of you, as opposed to those that you have to seek out or "make happen." Best of luck in your endeavors.

Reply
vivian mower
7/19/2017 09:14:04 am

I cannot find any peer-reviewed randomized, double-blind clinical tests which show Dr. Walsh's nutrient power to be more effective than placebo. All Dr. Walsh's claims are based on self-reporting ("I feel so much better". This is not science. Vivian Mower

Reply
Michele
2/9/2019 07:21:39 pm

Vivian, there are 1,000’s upon 1,000’s of patients, and probably more - who have greatly benefited from Dr Walsh’s work regarding mental health issues. Also many found the work of Dr Walsh as a “last resort” effort for help. His research and treatment is clinically precise; he does have a database of well over 30,000 patients and has a patent for his treatment for autism. The research IS there, yet as Courtney stated - it may not be exactly the same as the money hungry pharmaceutical industries double blind studies simply due to the facts Courtney already stated. Let me add - my son who was dx with bipolar saw over 10
MD’s who misdx AND mistreated him for over 4 years before we found Mensah Medical
Who closely work with Walsh. My son was tested; significant biochemical errors were found; he began treatment and within a month showed a positive response.
His recovery wasn’t easy. We retested; we adjusted nutrients; we had to treat his allergies with SLIT (sublingual immunology therapy) BEFORE he was able to respond to his nutrients... every month under Walsh’s/Mensah treatment he improved. Severe UM; copper/zinc imbalance). It’s been almost
Ten years. His brain chemistry? NORMAL! Yep - because of this brilliant research that we applied. If you saw his test results when he was 7 you would be shocked as well as his moods/ behaviors - out of control! Life was HELL! The work of Walsh and our doctors at Mensah have changed EVERYTHING while the 10+ MD’s we worked with ( who used research of double blind studies) three my son into mania multiple times; had him drugged up
On a “cocktail” of psychiatric meds AND the last straw was when the drug Abilify caused Tardive Dyskinesia a potentially IRREVERSIBLE disorder of facial twitching and grimacing. Thank God we found Walsh’s work and Dr Mensah/Bowman. I am writing a book on our experiences to save others the heartache we once lived!!!

Reply
Courtney Snyder link
8/2/2017 08:55:23 am

Hi Vivian - That's correct, you won't find any peer-reviewed randomized, double-blind clinical tests which show Dr. Walsh's nutrient protocols to be more effective than placebo. As I indicated in this blog post above, "the standards of current research (which) address one variable at a time. Our bodies and biochemistry are more complicated than this model allows. Rarely does someone have just one nutrient imbalance. Nutrient protocols/treatments are individualized and involve multiple nutrients/multiple variables which is quite different from one medication to treat one disorder. This later type of research makes even less sense when you understand that one disorder, for example, depression, is actually 5 different disorders." Also, as I mention above is the cost of such studies. They are exceedingly expensive - not necessarily for pharmaceutical companies, but for researchers not funded by corporations. I wish their was better evidence from a strict scientific model.

Reply
Nancy Trees
10/28/2017 11:19:02 pm

It might be interesting to you to talk with Dr Joan Larson of Health Recovery Center Minnespolis

Reply
anonymous
7/26/2021 03:23:52 pm

very informative blog. if one self-suspects a copper overload (or that they might have had one) and started taking zinc a few months ago (not more than 6 months probably less) gradually having increased from a small amount at first to the recommended daily average, then to maybe twice that then to about 50 per day (still not the highest that Walsh has some people do) then back down to around the recommended daily average (maybe more), how do they determine when to either stop the zinc supplements, or what exact dose to use? if acne is still present does that mean there is still a zinc deficiency?

thanks

Reply
Courtney Snyder, MD link
7/30/2021 02:09:57 pm

Thank you. I'm usually measuring zinc levels to determine dosing. As far as duration, it depends - if someone has a genetic vulnerability to copper overload, they may need to continue zinc supplementation. If someone has copper overload because of high copper exposure or high even a toxic exposure that is overwhelming the antioxidant that regulates zinc and copper - and those are addressed, their vulnerability to high copper would lessen and they may not continue to need zinc supplementation. Acne can be related to a number of factors beyond zinc (hormonal being exacerbated by environmental or physiologic stress, candida/mold, food sensitivities and more). Zinc can be important in mitigating some of these, but often there is more at play.

Reply
Amanda Cline
6/26/2024 05:25:36 am

Hi Courtney,

I happened upon your site the other day and I cannot tell you what a gift it is. The RCCX theory is an epiphany! I am curious, what is the antioxidant you refer to that regulates zinc and copper? I have high copper and mold toxicity, and zinc supplementation does not seem to be lowering the copper or free copper.

Many thanks.

Courtney Snyder MD link
7/16/2024 05:42:04 am

Amanda. I hope you see this. For some reason, I'm unable to reply under your comment. I'm glad you're finding my website helpful. The treatment I believe I was referencing was Metallothionein Promotion Therapy, which is a formula that Dr. Walsh designed. If you are working with a Walsh trained practitioner, they will be knowledgeable. It does require having zinc at a certain level and is usually started very slowly, as it can for be quite powerful and aggravate symptoms if started to quickly. I usually don't use this unless someones copper isn't coming down despite having zinc at optimal levels and also being on molybdenum, which also brings down copper. It too can be quite powerful, so monitoring (to make sure copper isn't getting too low) becomes important. Usually as with zinc, this is increased very slowly. If you're not already working with a Walsh trained practitioner, there is a resource map on the Walsh Research Institute website. Thank you for your comment and question.


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