By Courtney Snyder, MD
A Conversation About High Copper, Low Zinc, Pyrrole Disorder & Methylation Imbalances - Symptoms, Traits, Testing & Treatment I recently had the pleasure of joining Annika Taylor, a holistic health practitioner, on the Nourished By Nature: Mind Body Wellness Podcast. After sharing my journey into holistic psychiatry and defining what it means, Annika and I explored the following topics:
We also discussed a recent finding by Dr. Walsh that undermethylation is on the rise in the population, while overmethylation appears to be decreasing. Related Resources: Annika Taylor - nourishedbynature.com Walsh Research Institute For links to specific topics address see links in the description above.
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By Courtney Snyder, MD
Protecting Our Brain Early Starting With Understanding the Role of Inflammation, Oxidative Stress, Insulin Resistance, a Potential Microbial Presence & APOe4 Alzheimer’s is a neurodegenerative disease that involves the gradual death of brain cells, leading to the loss of brain tissue. The changes in the brain that lead to Alzheimer’s dementia can start up to 20 years before symptoms appear. This is crucial because emerging research and clinical experience in functional medicine suggest that many of the contributing factors can be influenced before symptoms progress. In this newsletter and podcast episode, I’ll explore:
In the next episode, I’ll delve into mainstream treatments and explore functional, integrative, and holistic approaches that target blood sugar regulation, oxidative stress, inflammation, and even mold and candida as potential contributors. Mentioned Resources: Other Related Newsletters: Medical Disclaimer: This newsletter is for educational purposes and not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment for either yourself or others, including but not limited to patients that you are treating (if you are a practitioner). Consult your own physician for any medical issues that you may be having.
In this video and podcast episode, I dive into pyrrole disorder, a common nutrient imbalance linked to various brain-related conditions affecting both adults and children. Elevated levels of Hydroxyhemopyrrolin-2-one (HPL) in the urine, often referred to as “pyrroles,” have been connected to conditions such as depression, anxiety, schizophrenia, bipolar disorder, autism, ADHD, learning disorders, substance use disorders, and even violent behavior.
In this discussion, I cover:
This episode is essential for understanding the role pyrrole disorder plays in mental health and how addressing it can lead to significant improvements in well-being. Related Resources
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Medical Disclaimer: This newsletter is for educational purposes and not intended or implied to be a substitute for professional medical advice, diagnosis or treatment for either yourself or others, including but not limited to patients that you are treating (if you are a practitioner). Consult your own physician for any medical issues that you may be having.
By Courtney Snyder, MD
Historically we've considered mental health and illness as coming from either one's life experiences or coming from one's genetics or biology. We've mistakenly considered the the brain separate from the rest of the body. We are more interconnected than those outdated views suggest. Our physical health impacts our brain health. Likewise, we experience emotions (fear, anger, sadness, and joy) not only in our brains, but in our bodies. Emotions influence our brain's biochemistry, and our biochemistry impacts our emotions, bodies and how we experience our lives. PYRROLE DISORDER A perfect example of this is Pyrrole Disorder - an inborn error of pyrrole chemistry. Those who are affected make an excessive amount of this metabolite. Pyrroles themselves are not a problem and do not cause disease. We all have them. They do however, bind Vitamin B6 and Zinc. When pyrroles leave the body (through urine), they take some B6 and zinc with them. This is not a problem either. The problem comes when pyrroles are being overproduced for genetic reasons or because of physical or emotional stress. This can lead to severe B6 and zinc deficiencies. Courtney Snyder, MD
Who knew...copper, the essential trace element important in the synthesis of neurotransmitters, respiration, immune function, energy metabolism and growth, could wreak so much havoc on the mind and body? I never gave much thought to copper until it presented itself to me in the most delightful way...a dream of a copper tiled ceiling - the most memorable dream I've had. Copper ... "associated with the goddess Aphrodite/Venus in mythology and alchemy, ...symbolic of love, balance, feminine beauty and artistic creativity." So taken with this dream, I painted a mantel copper. We eventually moved and left that copper mantel and dream behind. Ten years later copper resurfaced at the Walsh Research Institute where Dr. William Walsh was teaching about copper overload - one of the most common biochemical imbalances found in brain related disorders. "In most persons, blood copper levels are kept in a narrow range through the action of metallothionein, ceruloplasmin, as well as other proteins. Unfortunately, many persons have a genetic inability to regulate copper levels and a serious copper overload can result." - William Walsh, PhD. |
Courtney Snyder, MDFor anyone experiencing brain symptoms. This blog (and weekly newsletter) is your guide to demystifying root causes and learning about surprising paths to healing. From a holistic - functional adult and child psychiatrist dedicated to helping people heal and thrive. Categories
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