The "Seat of the Soul," Our "Dreaming Neurotransmitter, Melatonin Synthesis, Relationship Between Cortisol & Melatonin, Brain Waves & Sleep Cycles.
There is a wealth of information about sleep. In this newsletter, I'll highlight aspects I find especially interesting and significant.
In a future newsletter, I will delve into tools and techniques for optimizing sleep.
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By Courtney Snyder, MD
A Conversation About High Copper, Low Zinc, Pyrrole Disorder & Methylation Imbalances - Symptoms, Traits, Testing & Treatment I recently had the pleasure of joining Annika Taylor, a holistic health practitioner, on the Nourished By Nature: Mind Body Wellness Podcast. After sharing my journey into holistic psychiatry and defining what it means, Annika and I explored the following topics:
We also discussed a recent finding by Dr. Walsh that undermethylation is on the rise in the population, while overmethylation appears to be decreasing. Related Resources: Annika Taylor - nourishedbynature.com Walsh Research Institute For links to specific topics address see links in the description above.
In this video and podcast episode, I dive into pyrrole disorder, a common nutrient imbalance linked to various brain-related conditions affecting both adults and children. Elevated levels of Hydroxyhemopyrrolin-2-one (HPL) in the urine, often referred to as “pyrroles,” have been connected to conditions such as depression, anxiety, schizophrenia, bipolar disorder, autism, ADHD, learning disorders, substance use disorders, and even violent behavior.
In this discussion, I cover:
This episode is essential for understanding the role pyrrole disorder plays in mental health and how addressing it can lead to significant improvements in well-being. Related Resources
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Medical Disclaimer: This newsletter is for educational purposes and not intended or implied to be a substitute for professional medical advice, diagnosis or treatment for either yourself or others, including but not limited to patients that you are treating (if you are a practitioner). Consult your own physician for any medical issues that you may be having.
By Courtney Snyder, MD
How Viewing Schizophrenia as a Single Condition Limits the Development and Recognition of Effective Treatments. “If things are not so good, you maybe want to imagine something better." John Forbes Nash, Jr. Many know John Nash, Jr. as the brilliant mathematician portrayed by Russell Crowe in the movie "A Beautiful Mind." While the film doesn’t stay true to Nash’s real story, it does effectively depict his descent into psychosis and severe chronic mental illness.
Schizophrenia affects 1 in 300 people, or about 24 million people worldwide (2.6 million in the U.S.), and remains the most treatment-resistant psychiatric condition.
In this newsletter, using Nash's story as a reference, I will discuss:
Most people with schizophrenia are not brilliant mathematicians or Nobel Laureates; many are homeless. I reference Nash's story because it is widely known and because he likely had the most common form of schizophrenia--undermethylation (shared by 70% of those with this condition). Here are my 10 insights on schizophrenia. By Courtney Snyder
One of the challenges of writing blog posts that explore root causes of brain related symptoms is that what we are learning is constantly evolving. There's so much we still and will never know. Another challenge - everything is interconnected. The best I can do is to write about these root causes separately. While some contributing factors can occur in parallel, one condition is often leading to other downstream conditions that themselves contribute to things like depressed mood, anxiety, mood swings, brain fog/inattention and so forth. Mold toxicity is a perfect example. It can contribute to Pyrrole Disorder due the stress it puts on the body. It can lead to elevated copper by overwhelming one of the antioxidants in the body that regulates copper. Because it interferes with the immune system, it can lead to a susceptibility to candida/yeast, Lyme and its co-infections. It also frequently worsens mast cell activation (see last post). I consider it a root of the roots. In my daily work, I find mold toxicity to be very common. Here’s why - Lunch with Dr. William Walsh - His Story, Discoveries & the Future of Nutrient-Based Psychiatry7/1/2016
Courtney Snyder, MD
I first met Dr. Walsh in the fall of 2014, at his second physician training course here in the US. At the time, I was uncertain how useful nutrients would be in my psychiatric practice. What I learned seemed too good to be true. Upon returning home, I gradually began evaluating and treating specific nutrient imbalances in adults and children with depression, ADHD, anxiety, bipolar disorder, autism and other conditions. To my repeated surprise, most patients - children and adults alike improved… significantly - some dramatically, including those whose symptoms had failed to respond to other treatments.
By Courtney Snyder, MD
Historically we've considered mental health and illness as coming from either one's life experiences or coming from one's genetics or biology. We've mistakenly considered the the brain separate from the rest of the body. We are more interconnected than those outdated views suggest. Our physical health impacts our brain health. Likewise, we experience emotions (fear, anger, sadness, and joy) not only in our brains, but in our bodies. Emotions influence our brain's biochemistry, and our biochemistry impacts our emotions, bodies and how we experience our lives. PYRROLE DISORDER A perfect example of this is Pyrrole Disorder - an inborn error of pyrrole chemistry. Those who are affected make an excessive amount of this metabolite. Pyrroles themselves are not a problem and do not cause disease. We all have them. They do however, bind Vitamin B6 and Zinc. When pyrroles leave the body (through urine), they take some B6 and zinc with them. This is not a problem either. The problem comes when pyrroles are being overproduced for genetic reasons or because of physical or emotional stress. This can lead to severe B6 and zinc deficiencies. |
Courtney Snyder, MDFor anyone experiencing brain symptoms. This blog (and weekly newsletter) is your guide to demystifying root causes and learning about surprising paths to healing. From a holistic - functional adult and child psychiatrist dedicated to helping people heal and thrive. Categories
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